Endocrine Abstracts

The characteristics of Cushing’s syndrome (CS) pathophysiology, the heterogeneity of its clinical presentation and the different patterns of ACTH and cortisol secretion independently of the cause make the diagnosis of ACTH-dependent CS a difficult task in some cases. Clinical symptoms are not always specific enough to establish the diagnosis. 1 mg DEX suppression is one of the most used tests for CS screening. Nocturnal salivary cortisol may be used, but its accuracy has ...

Bariatric surgery has become the most effective therapeutic option for morbid obesity (BMI > 40 or >35 with major complications). All established surgical techniques are followed by significant body weight reduction as well as clear improvement /remission of main obesity-associated comorbidities such as type 2 diabetes (DM2), dyslipidaemia, hypertension, sleep apnoea and cardiac dysfunction. Mixed restrictive-malabsorptive techniques, such as Roux-en Y-gastric bypass (...